Demonstration Programs

Products

Terms and conditions

Quotations and Orders

 

Demonstration Programs

Demonstration programs are available on request. To prevent unauthorised use of our programs, it will not be possible to save results files. However, the full facilities will be available for evaluation. The user-friendly nature of the graphics interface and the potential benefits of these programs will be apparent.

To obtain your demonstration programs please e-mail PPL at:

  information@positiveprobability.com

 

Products

A. Products

General

Enchant Automatic Noise Reduction Algorithm

Enhance Fast Data Reconstructions

Nadir Baseline Correction

Sleuth 1-D Peak Detection/Deconvolutions & Reconstructions including variable peak width provcessing

Profile Automatic Modelling/Remodelling Program including variable peak width processing

Evaluate™ Quantification with Errors. Significance/Confidence filtering and Noise Rejection for Centroids and Deconvolutions

ReView User Graphics Interface

 

Mass Spectrometry

Locator Fast Reconstruction Centroiding

Discharge™ ESIMS Charge Deconvolutions for any mass

Collapse Deisotoping for Centroids and Deconvolutions

Element ICP-MS Analysis for Profile and Centroid Data

LCMS-HiRes Analysis Software where deisotoping is required to m/z or Zero-Charge

LCMS-LoRes Analysis Software for ESI Data where Isotopes are Unresolved

LCMS-View 2D Data Results Viewer

LCMS-Mapper Map Comparison Program

 

B. Licences

All PPL software packages are covered by a license for use on the single computer where the software is resident. Multiple computer discounts and site licenses are available by negotiation.

 

C. Standard Packages

PPL currently offers the following packages:

General

Data Deconvolutions (Part No. G-01)

This is a general purpose package for pre-processing and enhancing spectroscopic and chromatographic data. Features include the ability to enhance S/N and resolution and to provide fully quantified results, along with robust errors.

The software package comprises baseline correction (Nadir), peak modelling (Profile), S/N enhancement (Enchant & Enhance), data deconvolution (Sleuth), quantification (Evaluate) and the PPL graphics interface (ReView).


Mass Spectrometry

Data Deconvolutions (Part No. MS-01)
This package provides all the fundamental programs for processing mass spectrometry data.

In addition to the general features of G-01, this package contains specialised programs for centroiding (Locator) and deisotoping (Collapse).

Charge Deconvolutions (Part No. MS-02)
In addition to the data deconvolution features of MS-01, this package contains Discharge for performing charge deconvolutions on small molecules up to large heterogeneous proteins and polymers.

ICP-MS Analysis (Part No. MS-03)
This is a specially designed package for the processing and analysis of ICP-MS data. A novel feature is the ability to identify new interferences.

The software includes baseline correction (Nadir), peak modelling (Profile), data deconvolution (Sleuth), fast reconstruction peak identification (Locator), probabilistic analysis (Element), quantification (Evaluate) and the PPL graphics interface (ReView).

LCMS Peptide/Small Molecule Analysis Software where Deisotoping is Required to m/z or Zero-Charge. (Part No. MS-04)
This is a stand-alone Windows program that is used to process the LC-MS data of peptides or other small molecules off-line on any PC. The program accepts data in text file format, performs co-adds, baseline corrections and deconvolutions using a variable model. Confidence filters may be applied to the peak tables that are then deisotoped to C12 m/z ions or zero-charge masses. Background ions are identified and rejected before deconvolving the retention time axis. Results of m/z (or mass), RT and intensity, along with all the errors are reported.


LCMS Analysis Software for ESI Data where Isotopes are Unresolved (Part No. MS-05)

This is a stand-alone Windows program that is used primarily to process the ESI LC-MS data of intact proteins or low resolution data off-line on any PC. The program accepts data in text file format, performs co-adds, baseline corrections and deconvolutions using a variable model. Confidence filters may be applied to the peak tables that are then charge-deconvolved to zero-charge masses. Background ions are identified and rejected before deconvolving the retention time axis. Results mass, RT and intensity, along with all the errors are reported.


LCMS 2D Data Viewer (Part No. MS-06)
This is a stand-alone Windows program that is used to view 2D LC-MS data. The data may be zoomed, thresholds applied and intensities displayed linearly or logarithmically using a colour scale. The viewer will also overlay results from the LC-MS Peptide/Small Molecule Processing Programs.


LCMS Map Comparison Program (Part No. MS-07)

This is a stand-alone Windows program that is used to compare LC-MS maps and report differences at any chosen significance/confidence level within the user-chosen constraints.

Discounts

Any mass spectrometry programs ordered with MS-01 MS-02 are offered at 50% discount.

PPL will also offer discounts to a limited number of groups that are prepared to collaborate with PPL on joint publications and/or to develop new products. Please e-mail us for full details.

 

Terms and Conditions

PPL does not sell software. It offers licenses to use its products.

General

  1. All PPL software is protected by copyright. Software must not be passed to any third party without the written approval of PPL.
  2. All software remains the property of PPL.
  3. Licences are granted for an indefinite period.

Payment

  1. The standard terms of payment are 100% within 30 days of the invoice date.
  2. Interest on outstanding payments will be charged at 2.5% per month or part thereof.
  3. Payment is to be made in G.B. pounds () by cheque or direct to PPL’s bankers. Payments accepted in other currencies at the prevailing exchange rate at payment date.

Delivery

  1. Unless requested otherwise, products available at the time of ordering will sent via e-mail.
  2. Delivery will be advised on the quotation for products still under development.

Warranty and Maintenance

  1. All software is warranted for 12 months following delivery. The warranty includes fixing of unforeseen bugs, unlimited help and advice by electronic means and any software updates released during the warranty period.
  2. Any work undertaken at the Customer's request not covered by the warranty will be charged at the user consultancy rate. Where travelling and accommodation expenses are incurred, these will be charged at cost.
  3. PPL is not responsible for the quality of results obtained by users or any financial loss caused by the use of its products.

Updates and Upgrades

  1. Users will be informed of updates, upgrades and new products through the PPL web site and/or by e-mail.
  2. As they become available, updates and upgrades will be made available to existing users at a charge of 100 (GBP).
  3. Specifications for new products will be advertised through the PPL web site and/or e-mail. New products will be offered to existing customers for 50% of the list price.

Consultancy

  1. The amount of work required will be agreed with customers before work commences.
  2. The consultancy rate for existing customers is 300 (GBP) per day plus expenses to be charged at cost.

Additional Charges

  1. Where appropriate, expenses will be charged at cost.
  2. Where appropriate, VAT will be added to all prices and charged at the rate current at the time of invoicing.

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Quotations and Orders

PPL has a very competitive pricing policy and offers substantial discounts based on the number of products purchased. Please e-mail us for your personal quotation based on your requirements at:

information@positiveprobability.com

For more information, or to place an order please use the above email address